Rheumaxil Joint Pain Cream

Additional Information

Rheumatoid arthritis is a chronic systemic autoimmune disease which primarily involves synovial joint pain, immobility, and stiffness. RA exhibits extreme variation, ranging from a mild, self-limiting disease to a rapidly progressive arthritis with extra-articular manifestations. Rheumatoid arthritis patients use a variety of different treatment options to reduce inflammation and alleviate pain and stiffness.

Rheumatoid arthritis is a systemic disease of evolving immune dysregulation that culminates in joint destruction and disability. The dominance of cytokines during rheumatoid arthritis development is dynamic. Pro-inflammatory cytokines such as tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, and IL-6 are important mediators of the perpetuation of the disease. The role of CD4+CD25+ T regulatory cells (Treg) in controlling the activity of Th17 and other T cell subsets has increasingly been validated in human patients.

Th17/Treg balance in the course of autoimmune diseases has significantly advanced our understanding of the pathogenesis of these disorders. IL-23 plays a role in the maintenance of Th17 cells. The principle by which pro-inflammatory cytokines are therapeutically targeted to abrogate the disease is well established, but it is yet to be translated into a reliable cure for patients.

The powerful ingredients in RHEUMAXIL possess anti-inflammatory properties, which reduce the inflammation and redness to a great extent by modulating TH17/Treg cells axis and normalizing excessive production of several cytokines such as TNFalpha, IL17, IL23, IL1 and IL6 without causing general immunosuppression. With the regular consumption of cream, there will be an excellent improvement in the stiffness and swelling experienced by patients with not only rheumatoid, but also other types of arthritis.