Refresh RR Anti Hang Over Tablet

Additional Information

Hangovers are a frequent, though unpleasant, experience among people who drink to intoxication. Symptoms of a hangover include fatigue, headache, increased sensitivity to light and sound, redness of the eyes, muscle aches, and thirst. Signs of increased sympathetic nervous system activity can accompany a hangover, including increased systolic blood pressure, rapid heartbeat, tremor, and sweating.

The alcohol itself isn’t actually all that toxic, but it is acetaldehyde, a byproduct of alcohol consumption, that is the real cause of hangovers. When alcohol is consumed, it is mainly converted into acetaldehyde by alcohol dehydrogenase in the liver. Acetaldehyde has been implicated in several side effects after alcohol consumption. The levels of acetaldehyde in the CNS have profound effects in mediating the reinforcing actions of ethanol.

Ability of acetaldehyde to form covalent adducts with various proteins may be responsible for altered liver function, neuro-inflammation and stomach irritation and acidity. Higher concentrations of acetaldehyde cause unpleasant after-effects such as fatigue, headache, nausea, vomiting, body ache, burning sensation in the stomach, and drowsiness.

Hangover symptoms can be prevented or significantly reduced if you help your body get rid of the acetaldehyde. Treatment with thiol compounds, like L-Cysteine, N-acetyl Cysteine, Alpha Lipoic acid and Glutathione reduce acetaldehyde induced adverse effects. Glutathione, which has been called “the Mother of All Antioxidants”, is a peptide composed of three important amino acids: cysteine, glycine, and glutamate. N-acetyl Cysteine is effective in removing oxidants produced by toxins and helps to reduce oxidative stress. Glutathione plays a key role in alcohol detoxification by “mopping up” acetaldehyde. And it’s been shown that regular alcohol exposure depletes glutathione.

N-acetyl Cysteine provides a source of Cysteine for de novo GSH biosynthesis under conditions in which GSH is severely depleted, and that restoration of GSH can be cytoprotective. It’s important to note that most standard glutathione supplements get broken down by the digestive tract and do not enter your bloodstream. So you’ll need to find a highly-absorbable form of glutathione using Phytosomes. N-acetyl Cysteine prevents the hepatocellular toxic effects associated with hangover symptoms to reduce them and alleviate the hangover effects of alcohol consumption.

Alcohol consumption causes deficiency of Folate, Riboflavin, Thiamine, due to diminished absorption through intestine and impaired utilization. The sequel of these vitamins deficiencies causes fatigue, irritability, loss of appetite, sleep disturbances, poor memory, and abdominal discomfort. These vitamin deficiencies also cause irritability, nerve damage, tingling in your arms and legs, blurry vision, nausea and vomiting, and delirium. The intake of Nicotinamide provides NAD+ in excess and thus corrects NADH/NAD+ abnormalities and prevents the ethanol induced hepatotoxicity. Hence it is required to replenish these vitamins for good health.

Alcohol use is known to cause deficiency of Vitamin C which is a known antioxidant which reduces the severity of hangovers by speeding up the metabolism of alcohol by the liver. Taking glutathione, N-acetyl Cysteine and Vitamin C before or during alcohol consumption blocks alcohol toxicity and the irritable side effects. Alpha Lipoic Acid is an antioxidant that could possibly be even more protective than Vitamin C. It is fat soluble and can easily cross the blood-brain barrier to prevent the brain related symptoms.

Ginger is soothing to the gastric mucosa, and it has hepato-protective, antioxidant and anti-inflammatory properties. Curcumin provides anti-oxidant and anti-inflammatory properties which protect the gastric mucosa from oxidative stress and inflammation.