Oxphos NRF1 BoosterEnergy Booster With Mitochondria

Additional Information

Every day, our cells are damaged by free radicals from natural processes like breathing and from pollution in environment and diet. Mitochondria deteriorate with age due to ongoing exposure to free radicals, which accelerate the destruction of cellular components. Common reasons for mitochondria deficiencies also include stress, aging, conditions that impair nutrient absorption and lifestyle. Pesticides, herbicides and other chemical pollutants cause oxidative stress hence damaging mitochondrial counts eventually develop lethargy, inflammation, autoimmunity and initiate damage to cells by excessive oxidation. Smoking causes damage to mtDNA and mitochondrial structure.

Mitochondria rely heavily on nutrients for energy production in cells. Mitochondrial health includes minimizing oxidative stress and providing mitochondrial support, including promotion of mitochondrial biogenesis. Caloric restriction slows aging primarily by lowering free radical production in mitochondria. The benefits of increased mitochondrial biogenesis and ATP availability are many, including the reduction of oxidative stress and age–related deterioration as well as improvements in metabolic function, energy level, exercise performance, body composition, cog­nitive function and lifespan.

Nrf1 is the protein that regulates the expression of genes involved in mitochondrial DNA transcription, translation and repair. Nrf1 functions as a transcription factor that activates the expression of some key metabolic genes regulating cellular growth, and nuclear genes required for mitochondrial respiration, and mitochondrial DNA transcription and replication. Efficiency of mitochondria can be optimized by strengthening electron transport chain system and supporting energy flow for better ATP (energy packet) production with rate-limiting nutritional factor in the electron transport chain.

The aim of the formulation is to produce new, more powerful mitochondria, and make you feel younger and more energetic from the inside. Supplementing for nutritional deficiencies targeted for mitochondrial health is an excellent way to fill these gaps. In addition, activation of Nrf1 with a blend of herbal ingredients will eventually support mitochondria to slow down cellular aging and increase cellular energy.Further, it is also necessary to prevent oxidative damage of mitochondria with the help of unique antioxidant herbs. Utilization of cofactor in multi-enzyme complexes that catalyzes oxidative decarboxylation of alpha-keto acids such as the pyruvate dehydrogenase complex eventually supports additional energy production.

Unique herbs also prevented the breakdown of NAD+ and therefore increased levels of NAD+ and SIRT1, a protein involved in both mitochondrial function and genesis, protect the mitochondria from cellular stress and prevent the loss of mitochondrial function. Detoxification with selected unique phytochemicals with herbal active principle improves endurance capacity and mitochondrial density by activating SIRT1 and PGC-1α. Other herbs cause increase in the activity of mitochondrial proteins (SIRT3, PGC-1alpha, and AMPK) involved in both the proper functioning of mitochondria and the generation of new mitochondria.