Magnesium Citrate Magnesium Capsule

Additional Information

Magnesium is an important regulator of Calcium and cellular pH balance. Magnesium is required for many oxidation-reduction and phosphorylation reactions, such as creatine phosphokinase, which acts as an ATP regenerator through formation of phosphocreatine; pyruvate dehydrogenase that oxidizes pyruvate, facilitating pyruvate transformation into acetyl coenzyme A; and hexokinase, which is a main component of glucose metabolism. All these reactions are crucial to energy production.

Magnesium achieves this through formation of ATP-Mg complexes that anchor substrates to the active site on enzymes, catalysing the reaction and speeding up metabolic pathways. Mg2+ transporters within the mitochondria have shown that mitochondria contain high amounts of Mg2+ that as well as influencing mitochondrial enzymes also activate and stabilize cytochrome c oxidase, which catalyses the final stage in aerobic respiration.

Magnesium also plays a role in regulating muscle contractions. Magnesium is one of the minerals required by human body for nerve transmission and muscle contraction, with putative benefits for musculoskeletal health. Muscle cramp is a sudden, painful, and sustained contraction of skeletal muscle fibers. Most people have experienced a muscle cramp. Cramps can sometimes be severe and disabling, requiring medical attention.

Cramps occur in altered physiologic states, such as pregnancy and exercise in metabolic and neurologic diseases. The recommended daily intake for Magnesium is 300-400 mg· per day for women and men. However, the modern diet and reverse osmosis water intake tends to lack natural sources of Magnesium, leading to a growing deficiency within the population.

Large populations have inadequate intakes of several key nutrients for musculoskeletal health, including magnesium. Magnesium supplementation is effective for idiopathic skeletal muscle cramps. Effects of magnesium supplementation is significant on specific functional outcomes, such as muscle performance, mobility, or limitations in activities of daily living (ADL).